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Home » Shop » Catalog Peptides » Neurokinins Neuromedins and Preproneuromedins » (Tyr5, D-Trp6,8,9, Lys-NH2 10)-Neurokinin A (4-10) [135306-85-3]

(Tyr5, D-Trp6,8,9, Lys-NH2 10)-Neurokinin A (4-10) [135306-85-3]

Name: (Tyr5, D-Trp6,8,9, Lys-NH2 10)-Neurokinin A (4-10) [135306-85-3]
Brand: AAPPTec
SKU: P11179
Availability: InStock

Catalog Number: P002069

Sequence: Asp-Tyr-D-Trp-Val-D-Trp-D-Trp-Lys-NH2

Synonym: Men 10376

CAS Number: [135306-85-3]

Molecular Weight: 1081.25

Molecular Formula: C₅₇H₆₈N₁₂O₁₀

* Refer to Certificate of Analysis for lot specific data (including water content).

Catalog #	Product Name	Unit	Price	Qty
P002069	(Tyr5, D-Trp6,8,9, Lys-NH2 10)-Neurokinin A (4-10) [135306-85-3]		$180.00	(Tyr5, D-Trp6,8,9, Lys-NH2 10)-Neurokinin A (4-10) [135306-85-3] quantity

Other Names: MEN 10376

Men 10376 is a potent and selective NK2 receptor antagonist (pA2 = 8.08, rabbit pulmonary artery). Displays > 250-fold selectivity over NK1 (pA2 = 5.66, guinea pig ileum) and NK3 (Ki > 10 mM, guinea pig brain). Active in vivo. Maggi, CA; et al., J. Pharmacol. Exp. Ther., 257, 1172, (1991); Bartho, L; et al., Br. J. Pharmacol., 105, 805, (1992); Subramanian, N; et al., Biochem. Biophys. Res. Commun., 200, 1512, (1994).

M.W.: 1081.25

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