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Azido Amino Acids

Azido amino acids are versatile building blocks in peptide synthesis. They are utilized in click chemistry, the copper catalyzed cycloaddition of an azido function with a alkyne. Click chemistry is quick, does not require special selective deprotection schemes and it does not produce byproducts. Click chemistry is especially well suited for forming staples and other cyclic peptide structures and for conjugating peptides with tags or other biomolecules. Fmoc-Lys(N 3 )-OH and Fmoc-Nva(N 3 )-OH can also be utilized as protected derivatives of lysine and ornithine respectively. The azido group is stable under acid or basic conditions but can be readily reduced to the primary amine.  The azido group is stable to TFA and piperidine.  Standard synthesis and cleavage protocols may be used for azido-containing peptides.

Showing all 14 results

  • Placeholder
    Catalog #Product NameUnitPriceQty
    UFA245(R)-N-Fmoc-2-(5′-azidopentyl)alanine [1191429-12-5]
  • (S)-N-Fmoc-2-(4'-azidobutyl)alanine [1050501-64-8]
    Catalog #Product Name
    UFA144(S)-N-Fmoc-2-(4′-azidobutyl)alanine [1050501-64-8]Please contact AAPPTec for a quotation.
  • (S)-N-Fmoc-2-(5'-azidopentyl)alanine [1191429-12-5]
    Catalog #Product NameUnitPriceQty
  • (S)-N-Fmoc-2-(6'-azidohexyl)alanine [1191429-14-7]
    Catalog #Product Name
    UFA146(S)-N-Fmoc-2-(6′-azidohexyl)alanine [1191429-14-7]Please contact AAPPTec for a quotation.
  • Fmoc-Abu(N3)-OH, Fmoc-Dab(N3)-OH [942518-20-9]
    Catalog #Product NameUnitPriceQty
    UFK120Fmoc-Abu(N3)-OH, Fmoc-Dab(N3)-OH [942518-20-9]
  • Fmoc-D-Abu(N3)-OH, Fmoc-D-Dab(N3)-OH [1263047-53-5]
    Catalog #Product NameUnitPriceQty
    UFK220Fmoc-D-Abu(N3)-OH, Fmoc-D-Dab(N3)-OH [1263047-53-5]
  • Fmoc-D-Lys(N3)-OH [1198791-53-5]
    Catalog #Product NameUnitPriceQty
    AFK245Fmoc-D-Lys(N3)-OH [1198791-53-5]
  • Fmoc-D-Orn(N3)-OH [1176270-25-9]
    Catalog #Product NameUnitPriceQty
    UFO230Fmoc-D-Orn(N3)-OH [1176270-25-9]
  • Fmoc-D-Pra-OH [220497-98-3]
    Catalog #Product NameUnitPriceQty
    UFG235Fmoc-D-Pra-OH [220497-98-3]
  • Catalog #Product NameUnitPriceQty
    UFA111Fmoc-Dap(N3)-OH [684270-46-0]
  • Fmoc-Lys(N3)-OH [159610-89-6]
    Catalog #Product NameUnitPriceQty
    AFK145Fmoc-Lys(N3)-OH [159610-89-6]
  • Fmoc-Lys(N3)-OtBu
    Catalog #Product NameUnitPriceQty
  • Fmoc-Nva(N3)-OH [1097192-04-5]
    Catalog #Product NameUnitPriceQty
    UFO130Fmoc-Nva(N3)-OH [1097192-04-5]
  • Fmoc-Pra-OH [198561-07-8]
    Catalog #Product NameUnitPriceQty
    UFG135Fmoc-Pra-OH [198561-07-8]