Secretin is a peptide hormone that regulates pH within thre duodenum by controling secretion of gastric acid and bicarbonate into the duodenum. It also plays a role in osmregulation. William F. Ganong, MD (2003). “26. Regulation of Gastrointestinal Function”. Review of Medical Physiology (Twenty-First ed.). New York: McGraw-Hill, Medical Pub. Div. ; Chu JY; et al., Mol. Cell. Biol., 27, 2499 (2007); Chu JY; et al., Proc. Natl. Acad. Sci. USA, 106, 15961 (2009).
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