This 14-mer prosaptide sequence is derived from the active neurotrophic region in the amino-terminal portion of the saposin C domain. TX14(A) has anti-allodynic properties in a rat model of gp120-induced tactile allodynia. Hiraiwa, M; et al. Proc. Natl. Acad. Sci. USA, 94, 4778, (1997); Campana, M; et al., FASEB J., 12, 307, (1998); Taylor, E; et al., J. Pharmacol. Exp. Ther., 295, 190, (2000); Calcutt, NA; et al., Anesthesiology, 93, 1271, (2000); Jolivalt, CG; et al., Eur. J. Pain, 12, 76, (2008).
M.W.: 1579.74
