This peptide is derived from the BH3 domain of Bak (Flu-BakBH3). It has high-affinity binding to the Bcl-XL protein that is essential for its death antagonist function. Wang, J. et al. Cancer Res.60, 1498 (2000); Juin, P. et al. Mol. Cell. Biol. 2, 6158 (2002).
Bak-BH3 is derived from the BH3 domain of Bak (Flu-BakBH3). It has high-affinity binding to the Bcl-XL protein that is essential for its death antagonist function. Wang, J. et al., Cancer Res., 60, 1498 (2000); Juin, P. et al., Mol. Cell. Biol., 2, 6158 (2002).
M.W.: 1724.95
