N-Boc-L-aspartic acid beta-benzyl ester
Other Names: Boc-L-Asp(OBzl)-OH
Catalog #: ABD110
CAS #: 7536-58-5
Formula: C16H21NO6
M.W.: 323.3
Boc-Asp(OBzl)-OH is the aspartic acid derivative commonly utilized in Boc SPPS. Aspartic acid residues are often important in peptide binding and solubility. The benzyl ester on the Asp sidechain is removed when the peptide is cleaved from the resin with strong acids such as HF, TFMSA, or TMSOTf. In solution phase, Asp(OBzl) can also be deprotected by hydrogenolysis.
