This fibronectin-binding peptide, derived from the second type I repeat of thrombospondin, is an inhibitor of the fibronectin-mediated interactions of cells with collagen in the extracellular matrix. It is completely conserved in the second type I repeats of mouse and human thrombospondin-1 and thrombospondin-2 from mouse and chicken. Sipes, JM; et al., J. Cell Biol., 121, 469, (1993); Shultz-Cherry, S; et al., J. Biol. Chem., 270, 7304, (1995).
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