Other Names: Sheep Myeloid Antimicrobial Peptide 29
This 29 amino acid sheep myeloid antimicrobial peptide 29 (SMAP 29) displays extremely high antimicrobial activity against Pseudomonas strains, other gram-negative bacteria, and multidrug-resistant pathogens. SMAP 29 is a broad-spectrum antibiotic cathelicidin, it is active in both low- and high-ionic-strength conditions, and induces significant morphological alterations in bacterial surfaces. It also has significant antiendotoxin activity and may provide leads for treating septic shock. Saiman, L; et al., Antimicrob. Ag. Chemother., 45, 2838, (2001); Giacometti, A; et al., Am. J. Respir. Crit. Care Med., 169, 187, (2004).
M.W.: 3256.03
