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SH2 Domain Ligand (5)

SHIP COLD
Catalog Number: P002458
Sequence: Biotin-LC-pTyr-Glu-Glu-Ile
Synonym: SH2 Domain Ligand (5)
Molecular Weight: 972.05
Molecular Formula: C41H62N7O16PS
* Refer to Certificate of Analysis for lot specific data (including water content).
Catalog #Product Name
P002458SH2 Domain Ligand (5)Please contact AAPPTec for a quotation.

SH2 domains bind to the conserved sequence of Glu-Glu-Ile following a phosphorylated Tyr. The native peptide may therefore be an extremely effective SH2 domain binding probe. It binds to Src SH2 domain with high affinity.  Eck, MJ; et al., Nature, 362, 87 (1993); Nam, N; et al., Bioorg. Med. Chem., 12, 779 (2004).

M.W.: 972.05