AGRP is coexpressed with neuropeptide Y in the adrenal gland, hypothalamus [Bäckberg, M et al. Brain Res. Mol. Brain Res. 125, 129 ( 2004)]. AGRP increases appetite and decreases metabolism and energy expenditure. Plasma levels of AGRP are elevated in obese humans [Katsuki, A et al. J. Clin. Endocrinol. Metab. 86, 1921, (2001] and polymorphisms in the AGRP gene have been linked to anorexia nervosa [Vink, T et al. Mol. Psychiatry, 6, 325 (2001)]
Molecular Weight: 2894.5


