[Lys1015,1024]-Thrombospondin-1 (1015-1024) is an integrin-associated protein (IAP/CD47) agonist peptide derived from the cell binding domain of thrombospondin-1 (TS1). The peptide has been shown to stimulate integrin-dependent cell functions, including platelet aggregation. Gao, A-G; et al., J. Cell Biol., 135, 533, (1996); Wang, X-Q; Frazier, WA; Mol. Biol. Cell, 9, 865, (1998); Hillery, CA; et al., Blood, 94, 302, (1999); Chung, J; et al., Blood, 94, 642, (1999); Wang, X-Q; et al., J. Cell Biol., 147, 389, (1999); Miyata, Y; et al., Clin. Cancer Res., 9, 1734, (2003); Fujimoto, T-T; et al., J. Biol. Chem., 278, 26655, (2003).
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