P4 Model 400

The Model 400 pilot production scale peptide synthesizer is designed to prepare pharmaceutical peptides consistently and efficiently on production scales.  The Model 400 Pilot Production Scale Synthesizer can utilize standard Boc or Fmoc protocols, or the user can develop custom protocols to optimize product purity and synthesis yield. Reagents and amino acids are accurately and precisely dispensed through separate measuring vessels equipped with adjustable liquid sensors.  The amino acids are preactivated in a preactivation vessel before transfer to the reaction vessel; this, thereby, eliminates side reactions between the resin-peptide and coupling reagents and produces a purer peptide product.  Thorough, efficient mixing in the reaction vessel is obtained by nitrogen bubbling and/or orbital shaking. 

Production Scale

The Model 400 pilot production scale peptide synthesizer is available in multiple configurations suitable for small (20 g to 100g resin-peptide), medium (100 g to 3 kg resin-peptide), or large scale (over 3 kg of resin-peptide) production.  AAPPTec will custom build the Model 400 peptide synthesizer to your specifications.

Model 400 Peptide Synthesizer

For additional information about the Model 400 Pilot Production Scale Peptide Synthesizer, please send an email to sales@aapptec.com.