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Urocortin II [398001-88-2]

Catalog Number: P002584
Sequence: Ile-Val-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Gln-Ile-Leu-Leu-Glu-Gln-Ala-Arg-Ala-Arg-Ala-Ala-Arg-Glu-Gln-Ala-Thr-Thr-Asn-Ala-Arg-Ile-Leu-Ala-Arg-Val-Gly-His-Cys-NH2
Synonym: Urocortin II, human
CAS Number: [398001-88-2]
Molecular Weight: 4449.31
Molecular Formula: C194H338N63O54S
* Refer to Certificate of Analysis for lot specific data (including water content).
Catalog #Product NameUnitPriceQty
P002584Urocortin II [398001-88-2]

Urocotin II (human) binds selectively to the type 2 CRF receptor (CRF-R2), with no appreciable activity on CRF-R1.  Lewis, K; et al., Proc. Natl. Acad. Sci. USA, 98, 7570 (2001); Reyes, T.M.; et al., Proc. Natl. Acad. Sci. USA, 98, 2843 (2001).  UrocortinII has pro-inflammatory effects in human intestinal cells via the CRHR2α receptor and may play an important role in the pathophysiology of colitis in humans. Moss, AC; et al., Gut, 56, 1210, (2007).

MW: 4449.31