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Parathyroid Hormone (1-34) [52232-67-4]

Catalog Number: P002261
Sequence: Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe
Synonym: Parathyroid Hormone (1-34), human
CAS Number: [52232-67-4]
Molecular Weight: 4117.8
Molecular Formula: C181H291N55O51S2
* Refer to Certificate of Analysis for lot specific data (including water content).
Catalog #Product NameUnitPriceQty
P002261Parathyroid Hormone (1-34) [52232-67-4]

Other Names: pTH (1-34); Teriparatide Acetate

pTH (1-34) is osteogenic, thus it is used in treating osteoporosis. Alcohol consumption may reduce its efficacy, so pTH (1-34) may be less effective in treating osteoporosis arising from chronic alcohol abuse. pTH (1-34) speeds healing of bone fractures, especially when it is used in combination with other agents such as bone morphogenetic protein 7 or calcitonin. The osteogenic activity appears to be related to activation of adenylate cyclase. pTH also activates phospholipase C.  pTH(1-34) also has potential for treating bone marrow depletion caused by chemotherapy or radiation treatment in cancer patients. Applied topically, pTH(1-34) is reported to be a safe and effective treatment for psoriasis.  Cosman, F., Curr. Opin. Endocrinol. Diabetes Obes., 15, 495 (2008); Morgan, EF; et al., Bone, 43, 1031 (2008); Holick, MF; et al., Br. J. Dermatol., 149, 370 (2003).

MW: 4117.8