Fmoc-Lys(Boc,Me)-OH [951695-85-5]

N-alpha-Fmoc-N-epsilon-Boc-N-epsilon-methyl-L-lysine

Other Names: Fmoc-L-Lys(Boc,Me)-OH; Fmoc-Lys(Me,Boc)-OH

Fmoc-Lys(Boc, Me)-OH is useful for preparing monomethylated histone fragments utilized in studying the regulatory roles of methylated histones.  Fmoc-Lys(Boc,Me)-OH can be coupled using standard activating procedures.  The Boc group on the side epsilon nitrogen atom is removed with TFA, usually at the same time as the peptide is cleaved from the resin.

Molecular Weight: 482.5

Technical Bulletin

References

AE McBride, PA Silver, Cell, 2001, 106, 5.

AJ Bannister, Cell, 2002, 109, 801.

Z-P Huang, et al., Amino Acids, 2007, 33, 85.

H Chi, et al., Amino Acids, 2014, 46, 1305.