N-(N-Fmoc-glycinyl)-N-(2,4-dimethoxybenzyl)glycine
The N-Dmb group disrupts hydrogen bonding in the peptide backbone and reduces aggregation. Incorporated into long or difficult peptides, N-Dmb dipeptides can improve peptide yield and purity. In SPPS the N-Dmb group is removed with TFA during peptide cleavage from the resin. Fmoc-Gly-(Dmb)Gly-OH was utilized in the preparation of a 61-amino acid peptide (Dr. S. Zahariev, et al. J. Pept. Sci. 2005, 11, 17-28).
![Fmoc-Gly-(Dmb)Gly-OH [848861-65-4]](https://www.peptide.com/wp-content/uploads/2019/06/53350-1.jpg)
