Fmoc-Asp(OtBu)-(Dmb)Gly-OH [900152-72-9]

The N-Dmb group disrupts hydrogen bonding in the peptide backbone and reduces aggregation. Incorporated into long or difficult peptides, N-Dmb dipeptides can improve peptide yield and purity.

In Fmoc-Asp(OtBu)-(Dmb)Gly-OH the Dmb protecting group prevents aspartimide formation and the subsequent formation of side products.

N-Dmb group is removed with TFA. Typically this occurs simultaneously with TFA cleavage of the peptide from the resin.

MSDS