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Fmoc-Asn(Trt)-OH [132388-59-1]

Catalog Number: AFN105
Synonym: Fmoc-Asn(Trt)-OH
CAS Number: [132388-59-1]
Molecular Weight: 596.7
Molecular Formula: C38H32N2O5
* Refer to Certificate of Analysis for lot specific data (including water content).
Catalog #Product NameUnitPriceQty
AFN105Fmoc-Asn(Trt)-OH [132388-59-1]

N-alpha-Fmoc-N-gamma-trityl-L-asparagine    >99%

Molecular Weight: 596.7

Fmoc-Asn(Trt)-OH prevents the possibility of the amide side chain from undergoing dehydration side reactions during activation, especially with carbodiimide reagents.  Fmoc-Asn(Trt)-OH dissolves readily in all standard peptide synthesis reagents, while Fmoc-Asn-OH is only somewhat soluble in NMP or DMF.  The trityl group is removed with TFA.  This reaction is usually complete within 1 hour at room temperature, but is slower when the Asn(Trt) residue in at the N-terminal of the peptide.  In these cases, the deprotection reaction should be extended to 2 hours.