Fmoc-ANP Linker [171778-06-6]

3-(Fmoc-amino)-3-(2-nitrophenyl)propanoic acid:

ANP-Linker, also referred to as FNPPA or 3-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(2-nitrophenyl)propanoic acid, is a fluorescent tool that has been used in diverse studies, examining aspects like enzyme kinetics and protein-ligand interactions. Its functionality extends to acting as an inhibitory agent for enzymes, showcasing its capacity to impede the functions of various enzymes like cyclooxygenase-2 (COX-2) and matrix metalloproteinase-2 (MMP-2). Furthermore, ANP-Linker has applications as a photo initiator in the polymerization of several polymers, including poly(methyl methacrylate). While the exact mechanism of action for ANP-Linker remains unclear, it likely involves inhibiting enzymes like COX-2 and MMP-2, and possibly interactions with proteins [1].

1. Dynamic combinatorial chemistry as a rapid method for discovering sequence-selective RNA-binding compounds. , McAnany, JD. and Miller, BL. 2019. Methods Enzymol. 623: 67-84. PMID: 31239058

MSDS