Calcitonin acts to reduce blood calcium. It inhibits calcium absorption by the intestines, inhibits calcium and phosphate reabsorption by the kidney tubules and inhibits bone reabsorption. Broadly, it protects against calcium loss from the bones during pregnancy and lactation, prevents hypercalcemia from absorption of calcium from meals, acts as a satiety hormone and has analgesic activity. Woodrow, JP; et al., Endocrinology, 147, 4010 (2006); Chelikani, PK; et al., Am. J. Physiol. Regul. Integr. Comp. Physiol., 293, R1798 (2007); Tsavaris, N; et al., Oncol. Rep., 16, 871 ( 2006).
MW: 3417.87