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BOP-Cl [68641-49-6]

Catalog Number: CXZ090
Synonym: BOP-Cl
CAS Number: [68641-49-6]
Molecular Weight: 254.6
Molecular Formula: C6H8ClN2O5P
* Refer to Certificate of Analysis for lot specific data (including water content).
Catalog #Product NameUnitPriceQty
CXZ090BOP-Cl [68641-49-6]

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride

Molecular Weight: 254.6

BOP-Cl is a highly effective reagent for the acylation of N-methyl amino acids.  It provides good yields with low epimerization. (C Van Der Auwera, MJO Anteunis, Int. J. Pept. Protein Res., 1987, 29, 574-588).  BOP-Cl is also an efficient reagent for coupling protected amino monothioacids to iminoamino acid residues to form thiopeptide bonds (HT Lee, JF Gallard, M Mayer, E Guittet, R Michelot, Bioorg. Med. Chem. 1996, 4, 2201-9.)


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