This peptide has a similar degree of hydrophobicity as native amyloid beta-protein, but does not readily adopt the beta-sheet conformation. It inhibits amyloid beta-peptide fibril formation and partially disaggregates preformed fibrils in vitro. Sato, C.; et al., Biochem. Biophys. Res. Commun., 226, 672, (1996).
MW: 1315.55