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6-Cl-HOBt, 1-Hydroxy-6-chloro-benzotriazole [26198-19-6]
Synonym: 6-Cl-HOBt, 1-Hydroxy-6-chloro-benzotriazole
CAS Number: [26198-19-6]
Molecular Weight: 169.57
Molecular Formula: C6H4ClN3O
* Refer to Certificate of Analysis for lot specific data (including water content).
1-Hydroxy-6-chloro-benzotriazole
Molecular Weight: 169.57
6-Cl-HOBt is an alternative to HOBt. The chlorine atom attached to the ring increases the acidity and the effectiveness as a leaving group of 6-Cl-HOBt compared to HOBt. Like HOBt, 6-Cl-HOBt efficiently suppresses racemization during coupling. Cl-HOBt can be used in place of HOBt with equal or superior results.
1-Hydroxy-6-chloro-benzotriazole Molecular Weight: 169.57 6-Cl-HOBt is an alternative to HOBt. The chlorine atom attached to the ring increases the acidity and the effectiveness as a leaving group of 6-Cl-HOBt compared to HOBt. Like HOBt, 6-Cl-HOBt efficiently suppresses racemization during coupling. Cl-HOBt can be used in place of HOBt with equal or superior results.
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