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2-Chlorotrityl Chloride Resin

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Catalog Number: RTZ001
Synonym: 2-Chlorotrityl Chloride Resin
* Refer to Certificate of Analysis for lot specific data (including water content).
Catalog # Product Name Unit Price Qty
RTZ001 2-Chlorotrityl Chloride Resin
$80.00

Other Names: 2-Cl-Trt chloride resin

2-Chlorotrityl chloride resin can be cleaved under extremely mild acid conditions that leave Boc/tBu based protecting groups in place.  Thus it is used to prepare protected peptide fragments.  Amino acids can be attached to 2-Cl-Trt chloride resin with very little or no racemization.  The steric bulk of 2-chlorotrityl chloride resin inhibits diketopiperazine formation, which can be a major side reaction in the synthesis of peptides with C-terminal proline.

100-200 mesh, 1% DVB  Typical substitution levels range from 0.3 mmol/g to 0.8 mmol/g.  Other substitutions, mesh sizes or crossling are available by request.

MSDS           Loading and Cleavage Procedures

SDS