About AAPPTec

AAPPTec LLC, located in Louisville, KY, USA, is the only company that provides a complete line of peptide products ranging from automated peptide synthesizers (research scale 0.005 - 5.0 g, single synthesis to multiple synthesis, 2-384 sequences, production scale, 5g to 50 kg). AAPPTec also provides related laboratory equipment and high quality reagents from monomers, resins, solvents, and reagents for all different peptides, peptoids, and PNA synthesis with very competitive prices. AAPPTec's products are designed to assist chemists in preparing and analyzing high quality peptides from research to semi-preparative and preparative scale. In addition, AAPPTec provides technical information and instruction for each step of peptide synthesis and purification. AAPPTec also offers custom peptides in quantities from mg to kg, from crude to 98% pure, all at an affordable price. Contact AAPPTec for all your synthesis needs.

We pride ourselves on our ability to create innovative quality Peptide Synthesizers designed to fit any need or budget.  Our automated peptide synthesizers are designed for use in research and multi scale production.  We offer a wide range of instruments.

  • New Titan centrifugal synthesizer
  • The Infinity 2400™ Microwave Peptide Synthesizer utilizes microwave heating to accelerate slow couplings due to aggregation or steric hindrance and ambient temperature during rapid couplings. The Infinity 2400™ can microwave up to 6 reaction vessels at one time. 
  • The Apex series peptide instruments can synthesize a single peptide or up to 96 different peptides simultaneously at the scale of 10mg to 1gram.  AAPPTec will soon unveil a new Apex model that produces peptide libraries in 96 well titer plates.
  • The Focus peptide synthesizer series is our most versatile line as it can be used in both small and large scale peptide synthesis and can synthesize a single peptide or up to 6 different peptides simultaneously.
  • The Model 400 series of peptide instruments utilizes state of the art technology to synthesize peptides on a multi kilogram scale with up to 250 Liter Reactors. 
  • Peptide synthesizers in the Titan series are specially designed for preparing split-mix combinatorial peptide libraries.
  • The Matrix series of peptide instruments is designed for high throuput production of peptide libraries.

We provide the highest quality Fmoc-amino acids, Boc-amino acids, unusual amino acids, coupling reagents and resins for peptide synthesis at competitive prices.  All of our protected and unprotected amino acids, substituted and unsubstituted resins, and reagents undergo rigorous quality control testing to ensure that our customers receive the finest chemicals.  AAPPTec amino acid products are typically greater than 99% pure chemically are 99.5+% enatomeically pure.  Go to AAPPTec's on-line chemical catalog.

AAPPTec provides custom peptide synthesis for research and industry globally, from research to cGMP and bulk production. Our knowledgeable chemists, who have over 60 years combined experience in preparing high quality custom peptides, utilize the latest methodologies to produce high purity peptides rapidly and efficiently. With our many years of experience, we guarantee we can provide custom peptide synthesis at low cost with quick delivery and can produce the most difficult custom peptides.  Go to Custom Peptide Synthesis

We provide thousands of biologically active peptides and substrates for the research community.  We also provide numerous API and Cosmetic peptides.  In addition we provide custom production of cGMP peptides at our facility.

Go to the on-line Peptide Catalog

Our latest product line is our Spirit Analytical HPLC columns and preparative HPLC columns for peptide, protein and small-molecule analysis and purification. 

We offer three types of Spirit HPLC columns:

AAPPTec is your one source for peptide production equipment.  We provide high quality laboratory equipment to further assist your laboratory in their research.

Our products include:

AAPPTec custom peptide synthesis services can provide custom peptide libraries for drug discovery, high-throughput screening and SAR studies, including alanine scans and truncation sets. Peptide libraries are provided in 96-well plates with approximately 2 µmol of lyophilized peptide in each well.

AAPPTec utilizes optimized protocols and chemistries in custom peptide synthesis to ensure consistent purity, quantity and quality, library-to-library and within each library.

Custom peptide library modifications include D-amino acids, unusual amino acids, biotin or fluorescent labeling, N-acylation or C-terminal amide.

Provide AAPPTec with the peptide sequences and we will prepare a quotation for your library. Custom peptide synthesis of peptide libraries typically is completed in 2-3 weeks. Typical delivery consists of lyophilized peptides in 96-well titer plates, peptide location table, and MS and HPLC data.

Parallel library  

AAPPTec now offers custom polyclonal antibodies and custom monoclonal antibodies.  Our services include preparing the antigen, growing the antibodies, purifying the antibodes by afinity column, and labeling.  AAPPTec offers several polyclonal antibody production packages and monoclonal antibody production packages to fill your custom antibody requirements.

Featured Product


A smart new peptide synthesizer providing the peptide chemist and user, for the first time, software which analyzes any sequence no matter how difficult and provides a protocol. Eclipse presents the user with a synthesis strategy in an easy to interpret graphical display.
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AAPPTec Custom Peptide Synthesis

Custom peptide synthesis services provided by AAPPTec are available in all scales, from milligram research scale to multi-kilogram production scale. AAPPTec provides single custom peptides, multiple peptides and custom peptide libraries in a timely manner at competitive prices. Custom peptide prices are as low as $4.60 per amino acid for simple peptides.
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Reduced levels of Substance P (SP), an endogenous neuropeptide endowed with neuroprotective and anti-apoptotic properties, have been found in brain and spinal fluid of Alzheimer’s disease (AD) patients.
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