HOBt hydrate [123333-53-9]
1-Hydroxybenzotriazole hydrate
Other Names: HOBt H2O
Catalog #: CXZ010
CAS #: 123333-53-9
Formula: C6H7N3O2
M.W.: 153.1
HOBt hydrate is utilized in solid phase peptide synthesis as an additive during amino acid activation and coupling to suppress racemization. It is reported that adding a small amount of HOBt to the Fmoc cleavage solution can suppress aspartimide formation. (T. Michels, et al., Org. Lett., 2012, 14, 5218-21) Anhydrous HOBt poses a risk of explosion, but HOBt hydrate is desensitized.
Products Similar to HOBt hydrate
Cat. # |
Product |
CXZ021 | Oxyma |
CXZ012 | HOAt |
CXZ096 | 6-Cl-HOBt |
CXZ015 | HOOBt |
CXZ022 | HOSu |