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Fmoc-Phe(3-CF3)-OH [205526-27-8]

N-Fmoc-3-trifluoromethyl-L-phenylalanine

Other Names: Fmoc-Phe(m-CF3)-OH; Fmoc-meta-trifluorophenylalanine

Catalog Number: UFF164

CAS Number: 205526-27-8

Formula: C25H20F3NO4

M.W.: 455.4

 

Fmoc-Phe(3-Cl)-OH

 

 

 

 

Fmoc-Phe(3-CF3)-OH is used to introduce 3-trifluoromethylphenylalanine residues into peptides by Fmoc solid phase peptide synthesis.  The Phe(3-CF3) reisdue has been utililized as an NMR probe for characterizing protein structure and reactivity (JC Jackson, JT Hammill, RA Mehl, J. Am. Chem. Soc., 2007, 129, 1160-6).

Trifluoromethylphenylalanines

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UHF162 H-Phe(2-CF3)-OH UBF162 Boc-Phe(2-CF3)-OH UFF162 Fmoc-Phe(2-CF3)-OH
UHF262 H-D-Phe(2-CF3)-OH UBF262 Boc-D-Phe(2-CF3)-OH UFF262 Fmoc-D-Phe(2-CF3)-OH
UHF164 H-Phe(3-CF3)-OH UBF164 Boc-Phe(3-CF3)-OH UFF164 Fmoc-Phe(3-CF3)-OH
UHF264 H-D-Phe(3-CF3)-OH UBF264 Boc-D-Phe(3-CF3)-OH UFF264 Fmoc-D-Phe(3-CF3)-OH
UHF133 H-Phe(4-CF3)-OH UBF133 Boc-Phe(4-CF3)-OH UFF133 Fmoc-Phe(4-CF3)-OH
UHF233 H-D-Phe(4-CF3)-OH UBF233 Boc-D-Phe(4-CF3)-OH UFF233 Fmoc-D-Phe(4-CF3)-OH

3-Substituted Phenylalanines

H-Phe(3-Br)-OH   Boc-Phe(3-Br)-OH   Fmoc-Phe(3-Br)-OH
H-D-Phe(3-Br)-OH   Boc-D-Phe(3-Br)-OH   Fmoc-D-Phe(3-Br)-OH
H-Phe(3-Cl)-OH   Boc-Phe(3-Cl)-OH   Fmoc-Phe(3-Cl)-OH
H-D-Phe(3-Cl)-OH   Boc-D-Phe(3-Cl)-OH   Fmoc-D-Phe(3-Cl)-OH
H-Phe(3-F)-OH   Boc-Phe(3-F)-OH   Fmoc-Phe(3-F)-OH
H-D-Phe(3-F)-OH    Boc-D-Phe(3-F)-OH   Fmoc-D-Phe(3-F)-OH
H-Phe(3-CN)-OH   Boc-Phe(3-CN)-OH   Fmoc-Phe(3-CN)-OH
H-D-Phe(3-CN)-OH   Boc-D-Phe(3-CN)-OH   Fmoc-D-Phe(3-CN)-OH
H-Phe(3-Me)-OH   Boc-Phe(3-Me)-OH   Fmoc-Phe(3-Me)-OH
H-D-Phe(3-Me)-OH   Boc-D-Phe(3-Me)-OH   Fmoc-D-Phe(3-Me)-OH
H-Phe(3-CF3)-OH   Boc-Phe(3-CF3)-OH   Fmoc-Phe(3-CF3)-OH
H-D-Phe(3-CF3)-OH   Boc-D-Phe(3-CF3)-OH   Fmoc-D-Phe(3-CF3)-OH

MSDS