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Boc-D-His(Dnp)-OH IPA [204125-02-0]

Nalpha-Boc-Nim-(2,4-dinitrophenyl)-D-histidine isopropyl alcohol solvate

Catalog #: ABH210

CAS #: 204125-02-0

Formula: C17H19N5O8 · C3H8O

M.W.: 481.5


Boc-D-His(Dnp)-OH IPA








Boc-D-His(Dnp)-OH is one of the D-histidine derivative often utilized in Boc SPPS.  It forms a stable solvate with isopropyl alcohol.  The Dnp group is not removed under acidic conditions, but is removed with nucleophiles such as thiophenol.  Usually the Dnp group is removed before the peptide is cleaved from the resin.  This allows the highly colored byproducts to be easily separated from the peptide.

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