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Boc-D-Ala-OH [7764-95-6]


Catalog #: ABA201

CAS #: 7764-95-6

Formula: C8H15NO4

MW: 189.2






Boc-D-alanine is the tert-butyloxycarbonyl protected derivative of D-alanine.  D-alanine is produced in bacteria, but not eukariotic cells.  D-Alalnine forms an important part of a peptide contained in the basal structure of many bacterial cell walls.  The antibiotic vancomycin selectively binds D-Ala-D-Ala of membrane peptides.  

The susceptibility of S. aurens to cationic antimicrobial peptides is reduced when the C2 positin on the glycerol phosphate of lipoteichoic acid is functioalized with D-alanine.

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