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Trp-substituted cationic antimicrobial peptides

Antimicrobial properties and interaction of two Trp-substituted cationic antimicrobial peptides with a lipid bilayer. Bi X, Wang C, Dong W, Zhu W, Shang D., J Antibiot (Tokyo)., 2014, Feb 5. doi: 10.1038/ja.2014.4. [Epub ahead of print] Tryptophan (Trp)...

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Antiviral potential of cathelicidins.

Antiviral potential of cathelicidins. Barlow PG, Findlay EG, Currie SM, Davidson DJ., Future Microbiol., 2014, 9, 55-73. doi: 10.2217/fmb.13.135. The global burden of morbidity and mortality arising from viral infections is high; however, the development of effective...

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Analgesic Effects of Huwentoxin-IV

Analgesic Effects of Huwentoxin-IV on Animal Models of Inflammatory and Neuropathic Pain. Liu Y, Wu Z, Tang D, Xun X, Liu L, Li X, Nie D, Xiang Y, Yi J, Yi J., Protein Pept Lett., 2014, 21, 153-8. DOI: 10.2174/09298665113206660119 Huwentoxin-IV (HWTX-IV), a peptide...

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CGRP Poentiates Anxiety-like Behaviors

CGRP inhibits neurons of the bed nucleus of the stria terminalis: implications for the regulation of fear and anxiety. Gungor NZ, Pare D., J Neurosci., 2014, 34, 60-5. doi: 10.1523/JNEUROSCI.3473-13.2014. The bed nucleus of the stria terminalis (BNST) is thought to...

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Peptide YY modulates taste reponsiveness

Modulation of taste responsiveness by the satiation hormone peptide YY. La Sala MS, Hurtado MD, Brown AR, Bohórquez DV, Liddle RA, Herzog H, Zolotukhin S, Dotson CD., FASEB J., 2013, 27, 5022-33. doi: 10.1096/fj.13-228064. Epub 2013 Sep 16. It has been hypothesized...

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Glycosylated endomorphin-2 analog is potent analgesic

Novel glycosylated endomorphin-2 analog produces potent centrally-mediated antinociception in mice after peripheral administration. Fichna J, Mazur M, Grzywacz D, Kamysz W, Perlikowska R, Piekielna J, Sobczak M, Sałaga M, Toth G, Janecka A, Chen C, Olczak J., Bioorg...

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