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Four residues of propeptide are essential for precursor folding of nattokinase.
Four residues of propeptide are essential for precursor folding of nattokinase.   Jia Y, Cao X, Deng Y, Bao W, Tang C, Ding H, Zheng Z, Zou G., Acta Biochim. Biophys. Sin (Shanghai). , 2014, 46, 957-64. Subtilisin propeptide functions as an intramolecular...
Glucagon-like peptide-1 induces formation of new elastic fibers in human cardiac fibroblasts
The anti-diabetic hormone glucagon-like peptide-1 induces formation of new elastic fibers in human cardiac fibroblasts after cross-activation of IGF-1R.   Qa'aty N, Wang Y, Wang A, Mao S, Vincent M, Husain M, Hinek A., Endocrinology, 2014, Oct...
Antibacterial Peptide Derived From Fish NK-lysin
NKLP27: A Teleost NK-Lysin Peptide that Modulates Immune Response, Induces Degradation of Bacterial DNA, and Inhibits Bacterial and Viral Infection. Zhang M, Li MF, Sun L, PLoS One, 2014, 9, e106543. NK-lysin is an antimicrobial protein produced by cytotoxic T...
Indolicidin Stabilizes Duplex DNA and Prevents DNA Replication and Transcription
Indolicidin Targets Duplex DNA: Structural and Mechanistic Insight through a Combination of Spectroscopy and Microscopy. Ghosh A, Kar RK, Jana J, Saha A, Jana B, Krishnamoorthy J, Kumar D, Ghosh S, Chatterjee S, Bhunia A,  ChemMedChem, 2014, 9, 2052-8....
Novel Cyclic Biphalin Analogue with Improved Antinociceptive Properties
Novel Cyclic Biphalin Analogue with Improved Antinociceptive Properties Adriano Mollica, Alfonso Carotenuto, Ettore Novellino, Antonio Limatola, Roberto Costante, Francesco Pinnen, Azzurra Stefanucci,Stefano Pieretti, Anna Borsodi, Reza Samavati, Ferenc...
Antibacterial Peptide from Bee Venom
Production of antibacterial peptide from bee venom via a new strategy for heterologous expression. Hou C, Guo L, Lin J, You L, Wu W., Mol Biol Rep. 2014 Sep 5. [Epub ahead of print] Honey bee is important economic insect that not only pollinates fruits and...
Neuropeptide SIFamide from Desert Locust Schistocerca grearia
Identification and distribution of SIFamide in the nervous system of the desert locust Schistocerca gregaria. Gellerer A, Franke A, Neupert S, Predel R, Zhou X, Liu S, Reiher W, Wegener C, Homberg U., J Comp Neurol. 2014 Sep 4. doi: 10.1002/cne.23671. [Epub...
Short Neuropeptide F is a Critical Factor for Initiating Insect Metamorphosis
Short neuropeptide F (sNPF) is a stage-specific suppressor for juvenile hormone biosynthesis by corpora allata, and a critical factor for the initiation of insect metamorphosis. Kaneko Y, Hiruma K., Dev Biol., 2014, 393, 312-9. Molting and metamorphosis are...
Correlation of plasma oxytocin with autistic symptom load
Oxytocin plasma concentrations in children and adolescents with autism spectrum disorder: correlation with autistic symptomatology. Taurines R, Schwenck C, Lyttwin B, Schecklmann M, Jans T, Reefschläger L, Geissler J, Gerlach M, Romanos M., Atten. Defic....
Peptide Inhibitors for Anti-inflammatory Therapy
Targeting human secretory phospholipase A2 with designed peptide inhibitors for inflammatory therapy. Wang P, Li Y, Shao Q, Zhou W, Wang K., J Drug Target., 2014 Sep 19:1-7. [Epub ahead of print] Phospholipase A2 (PLA2) is potentially an important target for...
Selective Agonists to Neuromedin U Receptors Types 1 and 2
Discovery of Selective Hexapeptide Agonists to Human Neuromedin U Receptors Types 1 and 2 Kentaro Takayama, Kenji Mori, Koji Taketa, Akihiro Taguchi, Fumika Yakushiji, Naoto Minamino, Mikiya Miyazato, Kenji Kangawa, and Yoshio Hayashi, J. Med. Chem., Articles ASAP...
The Cu2+ Binding Properties of Branched Peptides Based on l-2,3-Diaminopropionic Acid
The Cu2+ Binding Properties of Branched Peptides Based on l-2,3-Diaminopropionic Acid Åukasz Szyrwiel , Åukasz Szczukowski, József S. Pap, Bartosz Setner, Zbigniew Szewczuk, and WiesÅ‚aw Malinka, Inorg. Chem., Article ASAP; Publication Date (Web): July 14,...
Oxytocin stimulates repair when muscle is damaged
Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration C Elabd, W Cousin, P Upadhyayula, RY Chen, MS Chooljian, J Li, S Kung, KP Jiang, IM Conboy, Nature Communications, 5, Article number:4082, Published on line 10...
Epinecidin-1 might have therapeutic use in Pseudomonas aeruginosa sepsis
Epinecidin-1 has immunomodulatory effects, facilitating its therapeutic use in a mouse model of Pseudomonas aeruginosa sepsis. CY Pan, JC Chen, JF Sheen, TL Lin, JY Chen, Antimicrob Agents Chemother. , 2014 May 12. [Epub ahead of print]...
Oxytocin and vasopressin modulate the social response to threat
Oxytocin and vasopressin modulate the social response to threat: a preclinical study. Mt Bowen, IS McGregor, Int J Neuropsychopharmacol. 2014 May 7:1-13. [Epub ahead of print] Individuals in many species increase their proximity to others in threatening...
Rattlesnake Toxin Crotamine Demonstrates Antifungal Activity
Interaction of the Rattlesnake Toxin Crotamine with Model Membranes. BA Costa, L Sanches, AB Gomide, F Bizerra, C Dal Mas, EB Oliveira, KR Perez, R Itri, N Oguiura, MA Hayashi, J Phys Chem B. , 2014 May 7. [Epub ahead of print] Crotamine is one of the main...
Trifluoroethanethiol: An Additive for Efficient One-Pot Peptide Ligation-Desulfurization Chemistry
Trifluoroethanethiol: An Additive for Efficient One-Pot Peptide Ligation-Desulfurization Chemistry RE Thompson , X Liu , N Alonso-Garcia , PJB Pereira , KA Jolliffe , RJ Payne, J. Am. Chem. Soc., Just Accepted Manuscript; Publication Date (Web): May 15,...
Recyclable, Racemization-free Coupling Reagent for Peptide Synthesis
Ethyl 2-cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate (o-NosylOXY): A Recyclable Coupling Reagent for Racemization free Synthesis of Peptide, Amide, Hydroxamate and Ester D Dev , NB Palakurthy , K Thalluri , J Chandra , B Mandal, J. Org. Chem., Just...
