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Identification and Functional Analysis of a Novel Tryptophyllin Peptide from the Skin of the Red-eye Leaf Frog, Agalychnis callidryas.
Identification and Functional Analysis of a Novel Tryptophyllin Peptide from the Skin of the Red-eye Leaf Frog, Agalychnis callidryas. Wang R, Zhou Y, Chen T, Zhou M, Wang L, Shaw C., Int J Biol Sci., 2015, 11, 209-19. Amphibian skin has proved repeatedly to be a...
Prevention of measles virus infection by intranasal delivery of fusion inhibitor peptides.
Prevention of measles virus infection by intranasal delivery of fusion inhibitor peptides. Mathieu C, Huey D, Jurgens E, Welsch JC, DeVito I, Talekar A, Horvat B, Niewiesk S, Moscona A, Porotto M., J Virol., 2015, 89, 1143-55. Measles virus (MV) infection is...
α,β-Dehydroamino acids in naturally occurring peptides
α,β-Dehydroamino acids in naturally occurring peptides Siodłak D., Amino Acids., 2015, 47, 1-17. α,β-Dehydroamino acids are naturally occurring non-coded amino acids, found primarily in peptides. The review focuses on the type of α,β-dehydroamino acids, the...
Fungicidal mechanisms of the antimicrobial peptide Bac8c.
Fungicidal mechanisms of the antimicrobial peptide Bac8c. Lee W, Lee DG., Biochim Biophys Acta., 2015, 1848, 673-9. Bac8c (RIWVIWRR-NH2) is an analogue peptide derived through complete substitution analysis of the linear bovine host defense peptide variant Bac2A. In...
Novel synthetic anti-fungal tripeptide effective against Candida krusei.
Novel synthetic anti-fungal tripeptide effective against Candida krusei. Gill K, Kumar S, Xess I, Dey S., Indian J Med Microbiol., 2015, 33, 110-6. INTRODUCTION: Candida species are the major fungal pathogens of humans. Among them, Candida krusei have emerged as a...
Antimicrobial Peptides with Potential for Biofilm Eradication
Antimicrobial Peptides with Potential for Biofilm Eradication: Synthesis and Structure Activity Relationship Studies of Battacin Peptides. De Zoysa GH, Cameron AJ, Hegde VV, Raghothama S, Sarojini V., J Med Chem. 2015, 58, 625-639. We report on the first chemical...
Detection of oxidative stress induced in Escherichia coli by the antimicrobial peptide CM15
Single-cell, real-time detection of oxidative stress induced in Escherichia coli by the antimicrobial peptide CM15 Choi H, Yang Z, Weisshaar JC, Proc Natl Acad Sci USA. 2015, 112, E303-E310. Antibiotics target specific biochemical mechanisms in bacteria. In response...
Depsipeptide Companeramides from a Panamanian Marine Cyanobacterium
Depsipeptide Companeramides from a Panamanian Marine Cyanobacterium Associated with the Coibamide Producer Oliver B. Vining, Rebecca A. Medina, Edward A. Mitchell, Patrick Videau, Dong Li, Jeffrey D. Serrill, Jane X. Kelly, William H. Gerwick,Philip J. Proteau, Jane...
Straightforward Synthesis of Novel Enantiopure α-Trifluoromethylated Azetidine 2-Carboxylic Acid and Homoserines
Straightforward Synthesis of Novel Enantiopure α-Trifluoromethylated Azetidine 2-Carboxylic Acid and Homoserines Nathalie Lensen, Joyce Marais, and Thierry Brigaud, Org. Lett., Article ASAP, Publication Date (Web): January 6, 2015 DOI: 10.1021/ol503448w The...
A potential agent against cryptococcosis
Synthesis of a new peptide-coumarin conjugate: a potential agent against cryptococcosis Soraya Z. Ferreira , Hellem C. Carneiro , Hugo A. Lara , Rosemeire B. Alves , Jarbas M Resende ,HeloÃsa M. Oliveira , Luciana M. Silva , Daniel A Santos , and Rossimirian P....
Ht31 peptide inhibited inflammatory pain
Ht31 peptide inhibited inflammatory pain by blocking NMDA receptor-mediated nociceptive transmission in spinal dorsal horn of mice. Wang WT, Pan GQ, Zhang ZY, Suo ZW, Yang X, Hu XD, Neuropharmacology, 2015, 89, 290-7. A kinase anchoring proteins (AKAPs) assemble...
Oxytocin increases empathy to pain when adopting the other- but not the self-perspective.
Oxytocin increases empathy to pain when adopting the other- but not the self-perspective. Abu-Akel A, Palgi S, Klein E, Decety J, Shamay-Tsoory S, Soc Neurosci. 2015 Feb;10(1):7-15. There is growing evidence that the neuropeptide oxytocin (OT) facilitates various...
Identification and distribution of SIFamide in the nervous system of the desert locust Schistocerca gregaria.
Identification and distribution of SIFamide in the nervous system of the desert locust Schistocerca gregaria. Gellerer A, Franke A, Neupert S, Predel R, Zhou X, Liu S, Reiher W, Wegener C, Homberg U, J. Comp. Neurol., 2015, 523, 108-25. SIFamides are a family of...
Analgesic Properties of a Galanin Analog
Analgesic Properties of a Peripherally Acting and GalR2 Receptor-Preferring Galanin Analog in Inflammatory, Neuropathic, and Acute Pain Models. Metcalf CS, Klein BD, McDougle DR, Zhang L, Smith MD, Bulaj G, White HS, J. Pharmacol. Exp. Ther., 2015, 352, 185-93. ...
Hydroxy-tryptophan containing derivatives of tritrpticin
Hydroxy-tryptophan containing derivatives of tritrpticin: Modification of antimicrobial activity and membrane interactions. Arias M, Jensen KV, Nguyen LT, Storey DG, Vogel HJ, Biochim Biophys Acta., 2015, 1848, 277-88. Tritrpticin is...
A Pseudomonas aeruginosa-Targeted Antimicrobial Peptide.
Importance of Tryptophan in Transforming an Amphipathic Peptide into a Pseudomonas aeruginosa-Targeted Antimicrobial Peptide. Zhu X, Ma Z, Wang J, Chou S, Shan A., PLoS One, 2014, 9(12), e114605. Here, we found that simple substitution of amino acids in the...
Ghrelin effects expression of several genes associated with depression-like behavior
Ghrelin effects expression of several genes associated with depression-like behavior Poretti MB, Rask-Andersen M, Kumar P, Rubiales de Barioglio S, Fiol de Cuneo M, Schiöth HB, Carlini VP, Prog Neuropsychopharmacol Biol Psychiatry, 2015, 56, 227-34. Ghrelin (Ghr) is...
A monomeric peptide triagonist corrects obesity and diabetes in rodents.
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents. Finan B, Yang B, Ottaway N, Smiley DL, Ma T, Clemmensen C, Chabenne J, Zhang L, Habegger KM, Fischer K, Campbell JE, Sandoval D,Seeley RJ, Bleicher K, Uhles S, Riboulet...
