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α,β-Dehydroamino acids in naturally occurring peptides

α,β-Dehydroamino acids in naturally occurring peptides SiodÅ‚ak D., Amino Acids., 2015, 47, 1-17. α,β-Dehydroamino acids are naturally occurring non-coded amino acids, found primarily in peptides. The review focuses on the type of α,β-dehydroamino acids, the...

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Fungicidal mechanisms of the antimicrobial peptide Bac8c.

Fungicidal mechanisms of the antimicrobial peptide Bac8c. Lee W, Lee DG., Biochim Biophys Acta., 2015, 1848, 673-9. Bac8c (RIWVIWRR-NH2) is an analogue peptide derived through complete substitution analysis of the linear bovine host defense peptide variant Bac2A. In...

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A potential agent against cryptococcosis

Synthesis of a new peptide-coumarin conjugate: a potential agent against cryptococcosis Soraya Z. Ferreira , Hellem C. Carneiro , Hugo A. Lara , Rosemeire B. Alves , Jarbas M Resende ,Heloísa M. Oliveira , Luciana M. Silva , Daniel A Santos , and Rossimirian P....

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Ht31 peptide inhibited inflammatory pain

Ht31 peptide inhibited inflammatory pain by blocking NMDA receptor-mediated nociceptive transmission in spinal dorsal horn of mice. Wang WT, Pan GQ, Zhang ZY, Suo ZW, Yang X, Hu XD, Neuropharmacology, 2015, 89, 290-7. A kinase anchoring proteins (AKAPs) assemble...

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Analgesic Properties of a Galanin Analog

Analgesic Properties of a Peripherally Acting and GalR2 Receptor-Preferring Galanin Analog in Inflammatory, Neuropathic, and Acute Pain Models. Metcalf CS, Klein BD, McDougle DR, Zhang L, Smith MD, Bulaj G, White HS, J. Pharmacol. Exp. Ther., 2015, 352, 185-93.  ...

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A Pseudomonas aeruginosa-Targeted Antimicrobial Peptide.

Importance of Tryptophan in Transforming an Amphipathic Peptide into a Pseudomonas aeruginosa-Targeted Antimicrobial Peptide. Zhu X, Ma Z, Wang J, Chou S, Shan A., PLoS One, 2014, 9(12), e114605.   Here, we found that simple substitution of amino acids in the...

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