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Stereocontrolled Construction of (E)-2-Amino-2-butenamide

Solid-Phase Total Synthesis of Bogorol A: Stereocontrolled Construction of Thermodynamically Unfavored (E)-2-Amino-2-butenamide Tomoya Yamashita, Takefumi Kuranaga, and Masayuki Inoue, Org. Lett., Article ASAP  Publication Date (Web): April 13, 2015  Copyright © 2015...

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Macrocyclic peptide with an unusual Lys-Trp crosslink

Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink Kelsey R. Schramma, Leah B. Bushin & Mohammad R. Seyedsayamdost, Nature Chemistry, 2015, 7, 431–437. Streptococcal bacteria use peptide signals as a...

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A potent peptide inhibitor of α-synuclein aggregation.

Intracellular screening of a peptide library to derive a potent peptide inhibitor of α-synuclein aggregation. Cheruvara H, Allen-Baume VL, Kad NM, Mason JM., J. Biol. Chem., 2015, First published on-line: January 23, 2015.  DOI: 10.1074/jbc.M114.620484 Aggregation of...

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CancerPPD: a database of anticancer peptides and proteins

CancerPPD: a database of anticancer peptides and proteins Atul Tyagi, Abhishek Tuknait, Priya Anand, Sudheer Gupta, Minakshi Sharma,Deepika Mathur, Anshika Joshi, Sandeep Singh, Ankur Gautam, Gajendra P.S. Raghava, Nucl. Acids Res. , 2015, 43, D837-D843. CancerPPD...

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Pachymodulin has Janus-like immunomodulatory capacities

Pachymodulin, a new functional formyl peptide receptor 2 (FPR2) peptidic ligand isolated from frog skin, has Janus-like immunomodulatory capacities Claire Lacombe, Christophe Piesse, Sandrine Sagan, Christophe Combadiere, Yvonne Rosenstein, and Constance Auvynet, J....

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Highly Angiogenic Peptide Nanofibers

Highly Angiogenic Peptide Nanofibers Vivek A. Kumar, Nichole L. Taylor, Siyu Shi,Benjamin K. Wang, Abhishek A. Jalan, Marci K. Kang, Navindee C. Wickremasinghe, and Jeffrey D. Hartgerink, ACS Nano, 2015, 9, 860-868. Major limitations of current tissue regeneration...

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Antidepressant-like effects of alarin

Antidepressant-like effects of alarin produced by activation of TrkB receptor signaling pathways in chronic stress mice. Wang M, Zhou W, Zhou X, Zhuang F, Chen Q, Li M, Ma T, Gu S., Behav. Brain Res., 2015, 280, 128-40. Alarin is a newly identified member of the...

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