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NGR Peptide Ligands Identified

NGR Peptide Ligands for Targeting CD13/APN Identified through Peptide Array Screening Resemble Fibronectin Sequences Rania Soudy , Sahar Ahmed , and Kamaljit Kaur * ACS Comb. Sci., Article ASAP DOI: 10.1021/co300055s Publication Date (Web): October 2, 2012 Copyright ©...

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Dolastatin 15 is a potential colon cancer drug

Dolastatin 15, a mollusk linear peptide, and Celecoxib, a selective cyclooxygenase-2 inhibitor, prevent preneoplastic colonic lesions and induce apoptosis through inhibition of the regulatory transcription factor NF-κB and an inflammatory protein, iNOS. Piplani H,...

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Soy tripeptide VPY reduces intestinal inflammation

The PepT1-transportable soy tripeptide VPY reduces intestinal inflammation. Kovacs-Nolan J, Zhang H, Ibuki M, Nakamori T, Yoshiura K, Turner PV, Matsui T, Mine Y., Biochim Biophys Acta., 2012, 1820, 1753-63. Epub 2012 Jul 27. DOI: 10.1016/j.bbagen.2012.07.007...

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Epitope mapping of swine fever virus glycoprotein E(rns)

New insights into the antigenic structure of the glycoprotein E(rns) of classical swine fever virus by epitope mapping. Meyer D, Aebischer A, Müller M, Grummer B, Greiser-Wilke I, Moennig V, Hofmann MA., Virology, 2012, 433, 45-54. doi: 10.1016/j.virol.2012.06.029....

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Anti-fungal peptide from ‘King Pole Bean’

A defensin-like peptide from Phaseolus vulgaris cv. 'King Pole Bean'. Wong JH, Ip DC, Ng TB, Chan YS, Fang F, Pan WL.,  Food Chem., 2012, 135, 408-14. Epub 2012 Apr 30. DOI: 10.1016/j.foodchem.2012.04.119 A 5447Da antifungal peptide with an N-terminal sequence highly...

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Flavor and flavor-enhancing peptides from peanuts

Isolation and identification of two novel umami and umami-enhancing peptides from peanut hydrolysate by consecutive chromatography and MALDI-TOF/TOF MS. Su G, Cui C, Zheng L, Yang B, Ren J, Zhao M., Food Chem. 2012, 135, 479-85. Epub 2012 May 2. DOI:...

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Peptide promotes bone marrow recovery after irradiation.

Fibroblast growth factor-Peptide promotes bone marrow recovery after irradiation. Ma J, Hou Y, Han D, Zhang M, Chen C, Zhang B, Zhang Z, Wang X, Yang S, Guo Y, Okunieff P, Zhang L., Adv Exp Med Biol. 2013, 765, 155-61. DOI: 10.1007/978-1-4614-4989-8_22 Various members...

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Fusion peptide target cancer cells

Selective killing of cancer cells by peptide-targeted delivery of an anti-microbial peptide. Sioud M, Mobergslien A. Biochem Pharmacol. 2012, 84, 1123-32. doi: 10.1016/j.bcp.2012.08.002. Epub 2012 Aug 14. Antimicrobial peptides selectively kill bacteria while...

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New antimicrobial peptide from tree shrew

A beta-defensin 1-like antimicrobial peptide from the tree shrew, Tupaia belangeri. Yang X, Dong L, Lv L, Yan X, Lai R, Liu R., Gene. 2012, 509, 258-62. doi: 10.1016/j.gene.2012.08.013. Epub 2012 Aug 24. A novel beta-defensin 1-like antimicrobial peptide (β-defensin...

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Anti-oxidant peptide from sweetpotatos

Defensin protein from sweet potato (Ipomoea batatas [L.] Lam 'Tainong 57') storage roots exhibits antioxidant activities in vitro and ex vivo. Huang GJ, Deng JS, Chen HJ, Huang SS, Liao JC, Hou WC, Lin YH., Food Chem. 2012 135, 861-7. Epub 2012 May 29. DOI:...

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New flavor peptides discovered

Isolation and identification of flavour peptides from Puffer fish (Takifugu obscurus) muscle using an electronic tongue and MALDI-TOF/TOF MS/MS. Zhang MX, Wang XC, Liu Y, Xu XL, Zhou GH.,  Food Chem. 2012, 135, 1463-70. Epub 2012 Jun 26. DOI:...

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Prophylactic Treatment in SOD Mutant Mouse Model of ALS

D-NAP Prophylactic Treatment in the SOD Mutant Mouse Model of Amyotrophic Lateral Sclerosis: Review of Discovery and Treatment of Tauopathy. Jouroukhin Y, Ostritsky R, Gozes I., J Mol Neurosci. 2012, 48, 597-602. DOI: 10.1007/s12031-012-9882-6 Davunetide (NAP) is a...

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Core – Shell Resins for Peptide Synthesis

Controllable Core―shell Type Resin for Solid-phase Peptide Synthesis Hong-Jun Cho , Tae-Kyung Lee , Jung Won Kim , Sang-Myung Lee , and Yoon-Sik Lee J. Org. Chem., Just Accepted Manuscript DOI: 10.1021/jo301716d Publication Date (Web): September 25, 2012 Copyright ©...

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Ultrasound Assissted Synthesis

Linear and Cyclic Amides with a Thiophene Backbone: Ultrasound Promoted Synthesis and Crystal Structures Thien Huynh Ngo , Huelya Berndt , Dieter Lentz , and Hans-Ulrich Reissig J. Org. Chem., Just Accepted Manuscript DOI: 10.1021/jo3017605 Full synthetic study of...

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