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Role of Pro residues in the selectivity of the helical antimicrobial peptide P5
The importance of being kinked: role of Pro residues in the selectivity of the helical antimicrobial peptide P5 Sara Bobone, Gianfranco Bocchinfuso, Yoonkyung Park, Antonio Palleschi, Kyung-Soo Hahm, Lorenzo Stella, J. Pept. Sci., 2013, 19, 758-769. DOI:...
An apolipoprotein E mimetic peptide with activities against multidrug-resistant bacteria and immunomodulatory effects
An apolipoprotein E mimetic peptide with activities against multidrug-resistant bacteria and immunomodulatory effects Chuan-qing Wang, Chang-sheng Yang, Yi Yang, Fu Pan, Lei-yan He, Ai-min Wang, J. Pept. Sci., 2013, 19, 745-750. DOI: 10.1002/psc.2570 Apolipoprotein E...
Short Antibacterial Peptides with Significantly Reduced Hemolytic Activity
Short Antibacterial Peptides with Significantly Reduced Hemolytic Activity can be Identified by a Systematic l-to-d Exchange Scan of their Amino Acid Residues. Albada HB, Prochnow P, Bobersky S, Langklotz S, Bandow JE, Metzler-Nolte N., ACS Comb Sci., 2013, 15,...
Antimicrobial activity of antihypertensive food-derived peptides
Antimicrobial activity of antihypertensive food-derived peptides and selected alanine analogues. McClean S, Beggs LB, Welch RW., Food Chem., 2014, 146, 443-7. doi: 10.1016/j.foodchem.2013.09.094. Epub 2013 Sep 25. This study evaluated four food-derived peptides with...
Anti-Candida activity of 1-18 fragment of the frog skin peptide esculentin-1b
Anti-Candida activity of 1-18 fragment of the frog skin peptide esculentin-1b: in vitro and in vivo studies in a Caenorhabditis elegans infection model. Luca V, Olivi M, Di Grazia A, Palleschi C, Uccelletti D, Mangoni ML. Cell Mol Life Sci. 2013 Nov 10. [Epub ahead of...
An insect defensin-derived β-hairpin peptide with enhanced antibacterial activity
An insect defensin-derived β-hairpin peptide with enhanced antibacterial activity Bin Gao, Shunyi Zhu, ACS Chem. Biol., 2013, Just Accepted Manuscript DOI: 10.1021/cb400591d Publication Date (Web): November 14, 2013 Copyright © 2013 American Chemical Society Insect...
Hydrogen Exchange-Mass Spectrometry Measures Stapled Peptide Conformational Dynamics
Hydrogen Exchange-Mass Spectrometry Measures Stapled Peptide Conformational Dynamics and Predicts Pharmacokinetic Properties Xiangguo (Eric) Shi, Thomas E. Wales, Carl Elkin, Noriyuki Kawahata, John R. Engen, D. Allen Annis, Anal. Chem., 2013, 85, 11185-11188. DOI:...
Synthesis and Evaluation of Novel Cyclic Peptide Inhibitors of Lysine-Specific Demethylase 1
Synthesis and Evaluation of Novel Cyclic Peptide Inhibitors of Lysine-Specific Demethylase 1 Isuru R. Kumarasinghe and Patrick M. Woster, ACS Med. Chem. Lett., 2013, Just Accepted Manuscript, DOI: 10.1021/ml4002997 Publication Date (Web): November 8, 2013 ...
Methanobactin-mediated one-step synthesis of gold nanoparticles.
Methanobactin-mediated one-step synthesis of gold nanoparticles. Xin JY, Cheng DD, Zhang LX, Lin K, Fan HC, Wang Y, Xia CG. Int J Mol Sci., 2013, 14, 21676-88. doi: 10.3390/ijms141121676. Preparation of gold nanoparticles with a narrow size distribution has enormous...
A Synthetic Peptide to Control Rice Blast Disease
PAF104, a Synthetic Peptide to Control Rice Blast Disease by Blocking Appressorium Formation in Magnaporthe oryzae. Rebollar A, López-GarcÃa B., Mol Plant Microbe Interact. 2013, 26, 1407-16. doi: 10.1094/MPMI-04-13-0110-R. Magnaporthe oryzae is the most devastating...
Modular assembly of dimeric HIV fusion inhibitor peptides with enhanced antiviral potency.
Modular assembly of dimeric HIV fusion inhibitor peptides with enhanced antiviral potency. Xiao J, Tolbert TJ., Bioorg Med Chem Lett., 2013, 23, 6046-51. doi: 10.1016/j.bmcl.2013.09.034. Epub 2013 Sep 20. The HIV-1 envelope gp120/gp41 glycoprotein...
Synthetic analogues of bovine bactenecin dodecapeptide reduce herpes simplex virus type 2 infectivity in mice.
Synthetic analogues of bovine bactenecin dodecapeptide reduce herpes simplex virus type 2 infectivity in mice. Shestakov A, Jenssen H, Hancock RE, Nordström I, Eriksson K. Antiviral Res., 2013, 100, 455-9. ...
Antimicrobial peptide Epinecidin-1 effective against MRSA infection in mice
Use of the antimicrobial peptide Epinecidin-1 to protect against MRSA infection in mice with skin injuries. Huang HN, Rajanbabu V, Pan CY, Chan YL, Wu CJ, Chen JY., Biomaterials., 2013, 34, 10319-27. doi:...
Short Analogs from Human Cathelicidin LL-37 Possess Antimicrobial and Antiendotoxic Activities
Short KR-12 analogs designed from human cathelicidin LL-37 possessing both antimicrobial and antiendotoxic activities without mammalian cell toxicity. Jacob B, Park IS, Bang JK, Shin SY., J Pept Sci., 2013, 19, 700-7. doi: 10.1002/psc.2552. KR-12 (residues...
Anti-bacterial Peptide has Potental in Anti-fungal Treatment
C. albicans growth, transition, biofilm formation, and gene expression modulation by antimicrobial decapeptide KSL-W. Theberge S, Semlali A, Alamri A, Leung KP, Rouabhia M., BMC Microbiol. 2013, 13, 246. Antimicrobial peptides have been the focus of much research over...
Novel α-Conotoxin that Potently Blocks α3β4 Nicotinic Acetylcholine Receptors
Characterization of a Novel α-Conotoxin TxIC from Conus textile that Potently Blocks rat α3β4 Nicotinic Acetylcholine Receptors Sulan Luo , Dongting Zhangsun , Xiaopeng Zhu , Yong Wu , Yuanyan Hu , Sean Christensen , Peta J. Harvey , Muharrem Akcan , David J Craik...
Minimum active structure of insulin-like peptide 5 (INSL5)
Minimum active structure of insulin-like peptide 5 (INSL5) Alessia Belgi , Ross A.D. Bathgate , Martina Kocan , Nitin Patil , Suode Zhang , Geoffrey W Tregear , John D. Wade , and Mohammed Akhter Hossain, J. Med. Chem., Just Accepted Manuscript DOI: 10.1021/jm400924p...
A Short Tryptophan-Rich Cationic Antimicrobial Peptide
Dynamic Turn Conformation of a Short Tryptophan-Rich Cationic Antimicrobial Peptide and its Interaction with Phospholipid Membranes Matthew Nichols , Miljan Kuljanin , Mostafa Nategholeslam , Tuan Hoang , Shaghayegh Vafaei , Bruno Tomberli , Chris G Gray , Lillian...
