Soluble Non-Crosslinked Poly(Norbornene) Supports for Peptide Synthesis with Minimal Reagents Nimmashetti Naganna and Nandita Madhavan, J. Org. Chem., Just Accepted Manuscript DOI: 10.1021/jo502197n Publication Date (Web): November 5, 2014 Copyright... Read more
Magainin 2 induces bacterial cell death showing apoptotic properties. Lee W, Lee DG., Curr. Microbiol., 2014, 69, 794-801. Magainin 2 is pore-forming antimicrobial peptide on lipid matrix of bacterial membrane, secreted from the skin of the African clawed frog... Read more
Peptide YY and ghrelin predict craving and risk for relapse in abstinent smokers. al’Absi M, Lemieux A, Nakajima M., Psychoneuroendocrinology, 2014, 49, 253-9. Appetite hormones are directly involved in regulating satiety, energy expenditure, and food intake,... Read more
Postsynthetic Modification of Unprotected Peptides via S-Tritylation Reaction Mochizuki M, Hibino H, Nishiuchi Y, Org. Lett., 2014 Articles ASAP (As Soon As Publishable) Tritylation using trityl alcohol (Trt–OH) in 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) is a... Read more
Postinfection Activity of Synthetic Antimicrobial Peptides Against Stemphylium vesicarium in Pear. Puig M, Moragrega C, Ruz L, Montesinos E, Llorente I., Phytopathology, 2014, 104, 1192-200. Brown spot of pear is a fungal disease of economic importance caused by... Read more
Dual function of a bee (Apis cerana) inhibitor cysteine knot peptide that acts as an antifungal peptide and insecticidal venom toxin. Park HG, Kyung SS, Lee KS, Kim BY, Choi YS, Yoon HJ, Kwon HW, Je YH, Jin BR., Dev. Comp. Immunol., 2014, 47, 247-53. Inhibitor... Read more
A hybrid cationic peptide composed of human beta-defensin-1 and humanized theta-defensin sequences exhibits salt-resistant antimicrobial activity. Olli S, Nagaraj R, Motukupally SR., Antimicrob. Agents Chemother., 2014, Oct 27. [Epub ahead of print] We have designed... Read more
Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer’s disease. McClean PL, Hölscher C., Neuropharmacology, 2014, 86, 241-58. Type 2 diabetes is a risk factor for developing Alzheimer’s... Read more
Antimicrobial activity of trout hepcidin. Alvarez CA, Guzmán F, Cárdenas C, Marshall SH, Mercado L., Fish Shellfish Immunol., 2014, 41, 93-101. Hepcidin is an antimicrobial peptide and a hormone produced mostly the liver. It is a cysteine-rich peptide with a highly... Read more