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Dolastatin 15 is a potential colon cancer drug

Dolastatin 15, a mollusk linear peptide, and Celecoxib, a selective cyclooxygenase-2 inhibitor, prevent preneoplastic colonic lesions and induce apoptosis through inhibition of the regulatory transcription factor NF-κB and an inflammatory protein, iNOS. Piplani H,... Read more

Soy tripeptide VPY reduces intestinal inflammation

The PepT1-transportable soy tripeptide VPY reduces intestinal inflammation. Kovacs-Nolan J, Zhang H, Ibuki M, Nakamori T, Yoshiura K, Turner PV, Matsui T, Mine Y., Biochim Biophys Acta., 2012, 1820, 1753-63. Epub 2012 Jul 27. DOI: 10.1016/j.bbagen.2012.07.007... Read more

Epitope mapping of swine fever virus glycoprotein E(rns)

New insights into the antigenic structure of the glycoprotein E(rns) of classical swine fever virus by epitope mapping. Meyer D, Aebischer A, Müller M, Grummer B, Greiser-Wilke I, Moennig V, Hofmann MA., Virology, 2012, 433, 45-54. doi: 10.1016/j.virol.2012.06.029.... Read more

Anti-fungal peptide from ‘King Pole Bean’

A defensin-like peptide from Phaseolus vulgaris cv. ‘King Pole Bean’. Wong JH, Ip DC, Ng TB, Chan YS, Fang F, Pan WL.,  Food Chem., 2012, 135, 408-14. Epub 2012 Apr 30. DOI: 10.1016/j.foodchem.2012.04.119 A 5447Da antifungal peptide with an N-terminal... Read more

Flavor and flavor-enhancing peptides from peanuts

Isolation and identification of two novel umami and umami-enhancing peptides from peanut hydrolysate by consecutive chromatography and MALDI-TOF/TOF MS. Su G, Cui C, Zheng L, Yang B, Ren J, Zhao M., Food Chem. 2012, 135, 479-85. Epub 2012 May 2. DOI:... Read more

Peptide promotes bone marrow recovery after irradiation.

Fibroblast growth factor-Peptide promotes bone marrow recovery after irradiation. Ma J, Hou Y, Han D, Zhang M, Chen C, Zhang B, Zhang Z, Wang X, Yang S, Guo Y, Okunieff P, Zhang L., Adv Exp Med Biol. 2013, 765, 155-61. DOI: 10.1007/978-1-4614-4989-8_22 Various members... Read more

Fusion peptide target cancer cells

Selective killing of cancer cells by peptide-targeted delivery of an anti-microbial peptide. Sioud M, Mobergslien A. Biochem Pharmacol. 2012, 84, 1123-32. doi: 10.1016/j.bcp.2012.08.002. Epub 2012 Aug 14. Antimicrobial peptides selectively kill bacteria while... Read more

New antimicrobial peptide from tree shrew

A beta-defensin 1-like antimicrobial peptide from the tree shrew, Tupaia belangeri. Yang X, Dong L, Lv L, Yan X, Lai R, Liu R., Gene. 2012, 509, 258-62. doi: 10.1016/j.gene.2012.08.013. Epub 2012 Aug 24. A novel beta-defensin 1-like antimicrobial peptide (β-defensin... Read more

Anti-oxidant peptide from sweetpotatos

Defensin protein from sweet potato (Ipomoea batatas [L.] Lam ‘Tainong 57′) storage roots exhibits antioxidant activities in vitro and ex vivo. Huang GJ, Deng JS, Chen HJ, Huang SS, Liao JC, Hou WC, Lin YH., Food Chem. 2012 135, 861-7. Epub 2012 May 29.... Read more

New flavor peptides discovered

Isolation and identification of flavour peptides from Puffer fish (Takifugu obscurus) muscle using an electronic tongue and MALDI-TOF/TOF MS/MS. Zhang MX, Wang XC, Liu Y, Xu XL, Zhou GH.,  Food Chem. 2012, 135, 1463-70. Epub 2012 Jun 26. DOI:... Read more

Prophylactic Treatment in SOD Mutant Mouse Model of ALS

D-NAP Prophylactic Treatment in the SOD Mutant Mouse Model of Amyotrophic Lateral Sclerosis: Review of Discovery and Treatment of Tauopathy. Jouroukhin Y, Ostritsky R, Gozes I., J Mol Neurosci. 2012, 48, 597-602. DOI: 10.1007/s12031-012-9882-6 Davunetide (NAP) is a... Read more