Stabilization of the Cysteine-Rich Conotoxin MrIA by Using a 1,2,3-Triazole as a Disulfide Bond Mimetic Alessandro Gori, Ching-I A. Wang, Peta J. Harvey, K. Johan Rosengren, Rebecca F. Bhola, Maria L. Gelmi, Renato Longhi, Macdonald J. Christie, Richard J. Lewis, Paul... Read more
Total Synthesis and Biological Evaluation of the Antibiotic Lysocin E and Its Enantiomeric, Epimeric, and N-Demethylated Analogues Motoki Murai, Takuya Kaji, Takefumi Kuranaga, Hiroshi Hamamoto, Kazuhisa Sekimizu and Masayuki Inoue, Ang. Chem. IEE, 2015, 54,... Read more
Highly Angiogenic Peptide Nanofibers Vivek A. Kumar, Nichole L. Taylor, Siyu Shi,Benjamin K. Wang, Abhishek A. Jalan, Marci K. Kang, Navindee C. Wickremasinghe, and Jeffrey D. Hartgerink, ACS Nano, 2015, 9, 860-868. Major limitations of current tissue regeneration... Read more
Haloganan: A novel antimicrobial peptide for treatment of wound infections Seo Hwa Shin, Bosung Kim, Seungmi Park, Sungho Jo, In Hee Lee, Peptides, 2014, 62, 137-143. HG1 is a Leu-rich antimicrobial peptide (AMP). Previously, the peptide was shown to lose its activity... Read more
Total Synthesis of the Cyclic Depsipeptide YM-280193, a Platelet Aggregation Inhibitor Harveen Kaur, Paul W. R. Harris, Peter J. Little, and Margaret A. Brimble, Org. Lett., 2015, 17, 492-495. The first total synthesis of YM-280193, a cyclic depsipeptide that inhibits... Read more
Effect of Size and N-Terminal Residue Characteristics on Bacterial Cell Penetration and Antibacterial Activity of the Proline-Rich Peptide Bac7 Filomena Guida, Monica Benincasa, Sotir Zahariev, Marco Scocchi, Federico Berti,Renato Gennaro, and Alessandro Tossi, J.... Read more
Cell-Permeable Cyclic Peptides from Synthetic Libraries Inspired by Natural Products William M. Hewitt, Siegfried S. F. Leung, Cameron R. Pye, Alexandra R. Ponkey, Maria Bednarek, Matthew P. Jacobson, and R. Scott Lokey, J. Am. Chem. Soc., 2015, 137, 715-721. Drug... Read more
Antidepressant-like effects of alarin produced by activation of TrkB receptor signaling pathways in chronic stress mice. Wang M, Zhou W, Zhou X, Zhuang F, Chen Q, Li M, Ma T, Gu S., Behav. Brain Res., 2015, 280, 128-40. Alarin is a newly identified member of the... Read more
Targeting the Neuropeptide Y System in Stress-related Psychiatric Disorders. Enman NM, Sabban EL, McGonigle P, Van Bockstaele EJ., Neurobiol Stress., 2015, 1, 33-43. Repeated, extreme, or traumatic stressors can elicit pathological effects leading to many negative... Read more
