Peptide

Peptide products from AAPPTec include Pharmaceutical Grade peptides and Cosmetic Grade peptides as well as over 2300 research grade peptides, in addition to custom peptides synthesis services. These are some of the types of peptides AAPPTec offers.

ACTH Amyloid Fragments
Angiotensins Bradykinins
Calcitonins CCK
Cone Snail Toxins Enkephalins
Glucagons GHRF
LHRH MSH
Natriuretic Peptides Neurokinins
Opioid Peptides PACAP
Substance P Vasopressins
VIP Virus Protein Fragments

 

To view AAPPTec's complete catalog of peptides, CLICK HERE

 

Custom Peptides
Custom peptides from AAPPTec are provided quickly and are competitively priced because AAPPTec’s chemists have up to 25 years experience in preparing high quality peptides. Using their experience our chemists prepare high purity peptides that minimize overall costs because less materials are used and less purification is required.  
AAPPTec can provide custom peptides containing up to 85 amino acids.  We utilize the latest proven methods, including sonication, reaction heating, pseudoprolines and Dmb-protected amino acids to produce high purity, high yield peptides, even of difficult sequences or modified sequences.
AAPPTec will provide custom peptides with the purity specifications you require. The purity levels listed below are the standard purity levels you may specify for your custom peptides.

Custom Peptides


Custom peptides from AAPPTec are provided quickly and are competitively priced because AAPPTec’s chemists have up to 25 years experience in preparing high quality peptides. Using their experience our chemists prepare high purity peptides that minimize overall costs because less materials are used and less purification is required.

 
AAPPTec can provide custom peptides containing up to 85 amino acids.  We utilize the latest proven methods, including sonication, reaction heating, pseudoprolines and Dmb-protected amino acids to produce high purity, high yield peptides, even of difficult sequences or modified sequences.
AAPPTec will provide custom peptides with the purity specifications you require. The purity levels listed below are the standard purity levels you may specify for your custom peptides.

Purity Applications
80% or greater Forming antibodies; tissue culture; ligand for affinity purification; non-quantitative antibody blocking experiments
90% or greater In vivo studies; bioassays; markers for electrophoresis; monoclonal antibodies
95% or greater ELISA;RIA: enzyme substrate
98% and above NMR; chromatography standards

 

Custom peptides can be provides as TFA salts as desalted peptides.

 

AAPPTec will prepare custom peptides containing unusual amino acids, isotopically labeled amino acids, cyclizations, side chain modifications, N-terminal and/or C-terminal modifications.  

 

Custom Peptide Modifications

AAPPTec can provide custom peptides with any of these modifications:

C-terminal Modifications

Acid (no modification)     Amide     Methyl ester     Benzyl ester     t-Butyl ester     Alcohol     Ketone

 

N-Terminal Modifications

No modification     Acetyl     Biotin     Fluorescent Dye     Fatty Acid     PEG

 

Cyclized Peptides

S – S Bridging (up to 3 disulfide bonds)     Head-to-tail cyclization     Sidechain cyclization     Stapled peptides

 

Phosphorylated Peptides

Tyr     Ser     Thr

 

Lysine Sidechain Modifications

Acetyl     Biotin     Methyl     Fluorescent Dye     PEG

 

Isotope Labeled Peptides

Ala (2H, 13C, 15N)     Arg (13C, 15N)      Asn (15N)     Asp (13C, 15N)     Glu (13C, 15N)     Gly (2H, 13C, 15N)

Ile (13C, 15N)      Leu (2H, 13C, 15N)      Lys (13C, 15N)     Met (13C, 15N)     Phe (2H, 13C, 15N)     Trp (15N)     Val (2H, 13C, 15N)

To download the AAPPTec Custom Peptide Brochure, CLICK HERE.

 

AAPPTec provides everything for solid phase peptide synthesis.

 
  • Quantities and Prices

    To obtain a quotation for custom peptide synthesis, click HERE or contact AAPPTec by e-mail at sales@aapptec.com.
  • Contact Us

    United States Contact Information

    Thank you for visiting our website and for your interest in our company! AAPPTec has a dedicated team of chemists, engineers, technical consultants, sales representatives, and customer service representatives whom are waiting to hear from you. We look forward to speaking with you and working with you on all of your peptide-related needs.

    Address: 6309 Shepherdsville Road Louisville, KY 40228-1027

    Toll-Free Telephone: (888) 692-9111

    Telephone: (502) 968-2223

    Emails: info@aapptec.com, sales@aapptec.com

    Fax: (502) 968-3338

    Business Hours: Monday-Friday, 8am-6pm EST

    AAPPTec has representative all over the world. For contact information on the representative nearest you, please go to www.aapptec.com.

  • About Us

    AAPPTec, located in Louisville, KY, USA, offers custom peptides in quantities from mg to kg, in purities from crude to 98%, all at an affordable price. In addition to standard peptides, we also provide custom peptides with modifications such as cyclization, phosphorylation, acetylation, fluorescent labels, etc.

    Our Production Team has decades of experience in preparing high quality peptides, including long peptides, difficult peptides and peptides with special modifications.

    Our Customer Support Team has many years of experience in the peptide business and they are ready to help you with questions, orders, etc.

    AAPPTec continually strives to provide the latest technology, the most competitive prices and the highest standard of customer support to peptide chemists worldwide.

    We welcome your suggestions regarding our products and customer support. Please tell us how we can better serve you.

    Please send your suggestions to info@aapptec.com

  • What's News

    For upcoming shows, click HERE For the AAPPTec newletter Peptide News, click HERE For recent publications about peptides and proteins, click HERE.
  • FAQ

    1. How do I request a quote for my peptide?

    To request an instant quote, please sign up a free account with us and proceed to the peptide order page. If you do not have an account with us yet and would like to receive a quote for your peptide(s), please email us: www.aapptec.com or call us at 1-888-692-9111 and ask for a peptide service representative.


    2. What type of chemistry do you use?

    AAPPTec generally utilizes Fmoc chemistry for most peptide production.


    3. How do you generally purify your peptides?

    Our peptides are generally purified by preparative reversed phase HPLC, using trifluoroacetic acid (TFA) modified buffers at pH 2. Buffer A is 0.1 % TFA deionized water and buffer B is 0.1 % TFA in acetonitrile (ACN) at pH 2. Peptides are dissolved in either straight buffer A, or some amount of buffer B then diluted with buffer A.

    Sometimes it is necessary to use an organic polar solvent like (formic acid or acetic acid) in DMSO or DMF to aid in the dissolving of hydrophobic peptides but this is done on a case-by-case basis depending on the sequence analysis. The separation is monitored by UV at 214 nm and fractions are collected and analyzed by mass spectrometry for product identity and by reversed phase analytical HPLC for purity.

    The fractions are then lyophilized to remove the solvents. The fractions that meet the specifications of the order are then combined into one vial. Next, we run a final mass spectrum and analytical HPLC on the combined material.

 
AAPPTec offers Custom Peptides Catalog Peptides Immunology Polyclonal Antibodies Monoclonal Antibodies Amino Acids Synthesis Resins Coupling Reagents Bulk Amino Acids Bulk Synthesiz resins Bulk Coupling Reagents Peptide Synthesizers Freeze Dryers HPLC Systems HPLC Columns AAPPTec is your one source for peptides and peptide synthesis.